Occurrence of Antibiotic Resistance Genes, Antibiotics-Resistant and Multi-Resistant Bacteria and Their Correlations in One River in Central-Western Brazil

(1) Background: The uncontrolled increase in pollutants the aquatic environment results antibiotic-resistant bacteria and antibiotic resistance genes (ARBs ARGs). overuse misuse of antibiotics is also a crucial factor for public health. (2) Methods: In this study, presence ARBs 24 from eight different classes were evaluated addition to performing statistical correlations intercorrelations. Samples water sediment collected river central-western Brazil, responsible supplying more than 3 million people. Physicochemical analyses performed on samples, as well methodological approaches based culture molecular biology, such real-time polymerase chain reaction (qPCR). (3) Results: analysis apparent color, turbidity, thermotolerant coliforms E. coli not accordance with Brazilian legislation. A total 203 bacterial strains isolated, which 30.54% Entero-bacteriaceae family 29.06% Staphylococcaceae family. For found, higher prevalence lyconsamides β-lactams was detected. Among all isolated strains, multi-drug profile 59.37% found. ARGs detected samples; searched, 22 sul2 ermC samples. According analysis, Meia Ponte River suffering great anthropogenic impact, current legislation sufficient prevent it. This serving reservoir genes, measures monitoring, depollution, management preservation must be taken, so that population does suffer damage. (4) Conclusions: first study State Goiás, indicate existence samples raw sediments, supporting worldwide investigation environment. addition, few studies address between groups, an important field antimicrobial resistance.